Prof. MUDr. Martin Matějovič, Ph.D.
I. interní klinika LF UK a FN Plzeň
Prof. MUDr. Martin Matějovič, Ph.D., absolvent lékařské fakulty UK v Plzni (1993), v letech 1997–1998 absolvoval část Ph.D. studia na univerzitě Ulm v Německu. Po svém návratu působil jako asistent LF UK na I. interní klinice LF a FN Plzeň a získal specializovanou způsobilost v oborech vnitřního lékařství a intenzivní medicíny. V roce 2004 byl jmenován docentem a v roce 2009 profesorem vnitřního lékařství. Od roku 2006 je přednostou 1. interní kliniky FN a LF UK v Plzni.
Profesor Matějovič je autorem nebo spoluautorem více než 250 publikací, jež byly více než 1000 krát citovány a 3 monografií. Je držitelem The European Society of Intensive Care Medicine Yearly Award a nositelem prestižních zahraničních stipendií (Alexander von Humboldt Research Fellowship a Boehringer Ingelheim Fonds Stiftung für Medizinische Grundlagenforschung). Profesor Matějovič je místopředsedou výboru České společnosti intenzivní medicíny, působil jako Council Member Evropské společnosti intenzivní medicíny (ESIM). Působí jako člen Vědecké rady Agentury pro zdravotnický výzkum České republiky a předseda Panelu Poruchy orgánových funkcí a úrazová a intenzivní medicína“.
Prof. MUDr. Martin Matějovič, Ph.D. je autorem těchto článků v časopise Postgraduální nefrologie:
Anazodo UC, Wong DY, Théberge Jean, et al. Hemodialysis‑Related Acute Brain Injury Demonstrated by Application of Intradialytic Magnetic Resonance Imaging and Spectroscopy. J Am Soc Nephrol 2023;34:1090–1104.
Miano TA, Hennessy S, Yang W, et al. Association of vancomycin plus piperacillin–tazobactam with early changes in creatinine versus cystatin C in critically ill adults: a prospective cohort study. Intensive Care Med 2022;48:1144–1155.
STARRT‑AKI Investigators, et al. Timing of Initiation of Renal‑Replacement Therapy in Acute Kidney Injury. N Engl J Med 2020;383:240–251.
Hayek SS, Leaf DE, Samman Tahhan A, et al. Soluble Urokinase Receptor and Acute Kidney Injury. N Engl J Med 2020;382:416–426.
Jaber S, Paugam C, Futier E, et al.; BICAR‑ICU Study Group. Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR‑ICU): a multicentre, open‑label, randomised controlled, phase 3 trial.
Lancet 2018;392:31–40.
Zhang Z, Zhu C, Mo L, Hong Y. Effectiveness of sodium bicarbonate infusion on mortality in septic patients with metabolic acidosis.
Intensive Care Med 2018;44:1888–1895
Semler MW, Self WH, Wanderer JP, et al.
Self WH, Semler MW, Wanderer JP, et al.
Bagshaw SM, Gibney RTN, Kruger P, et al.
The effect of low dose furosemide in critically ill patients with early acute kidney injury: A pilot randomized blinded controlled trial (the SPARK study). J Crit Care 2017;42:138–146.
Nijssen EC, Rennenberg RJ, Nelemans PJ, et al.
Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast‑induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open‑label, non‑inferiority trial. Lancet 2017;389:1312–1322.
Zarbock A, Kellum JA, Schmidt C, et al. Initiation Strategies for Renal‑Replacement Therapy in the Intensive Care Unit. N Engl J Med 2016;375:122–133.
Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mortality in Critically Ill Patients With Acute Kidney Injury: The ELAIN Randomized Clinical Trial. JAMA 2016;315:2190–2199.
Sun LY, Wijeysundera DN, Tait GA, Beattie WS. Association of intraoperative hypotension with acute kidney injury after elective noncardiac surgery. Anesthesiology 2015;123:515–523.
Koyner JL, Davison DL, Brasha‑Mitchell E, et al. Furosemide stress test and biomarkers for the prediction of AKI severity. J Am Soc Nephrol 2015;26:2023–2031.
Gattas DJ, Rajbhandari D, Bradford C, et al. A randomized controlled trial of regional citrate versus regional heparin anticoagulation for continuous renal replacement therapy in critically ill adults. Crit Care Med 2015 Apr 6 [Epub ahead of print].
Stucker F, Ponte B, Tataw J, et al. Efficacy and safety of citrate‑based anticoagulation compared to heparin in patients with acute kidney injury requiring continuous renal replacement therapy: a randomized controlled trial. Crit Care 2015;19:91.
Angeli P, Gines P, Wong F, et al. Diagnosis and management of acute kidney injury in patients with cirrhosis: revised consensus recommendations of the International Club of Ascites. J Hepatol 2015 Jan 27. pii: S0168‑8278(14)00958‑1. doi: 10.1016/j.jhep.2014.12.029.
Dlouhodobé důsledky intermitentních a kontinuálních metod náhrady funkce ledvin u kriticky nemocných
Wald R, Shariff SZ, Adhikari NK, et al. The association between renal replacement therapy modality and long‑term outcomes among critically ill adults with acute kidney injury: a retrospective cohort study. Crit Care Med 2014;42:868–877.
Muriithi AK, Nasr SH, Leung N. Utility of urine eosinophils in the diagnosis of acute interstitial nephritis. Clin J Am Soc Nephrol 2013;8:1857–1862.
Joannes‑Boyau O, Honoré PM, Perez P, Bagshaw SM, Grand H, Canivet JL, Dewitte A, Flamens C, Pujol W, Grandoulier AS, Fleureau C, Jacobs R, Broux C, Floch H, Branchard O, Franck S, Rozé H, Collin V, Boer W, Calderon J, Gauche B, Spapen HD, Janvier G, Ouattara A. High‑volume versus standard‑volume haemofiltration for septic shock patients with acute kidney injury (IVOIRE study): a multicentre randomized controlled trial. Intensive Care Med 2013;39:1535–1546.
Markota D, Markota I, Starcevic B, Tomic M, Prskalo Z, Brizic I. Prevention of contrast‑induced nephropathy with Na/K citrate. Eur Heart J 2013;34:2362–2367.
Pons B, Lautrette A, Oziel J, Dellamonica J, Vermesh R,
Ezingeard E, Mariat C, Bernardin G, Zeni F, Cohen Y, Tardy B,
Souweine B, Vincent F, Darmon M. Diagnostic
accuracy of early urinary index changes in differentiating
transient from persistent acute kidney injury in critically ill
patients: multicenter cohort study. Crit Care
2013;17:R56.
Rachoin JS, Daher R, Moussallem C, Milcarek B, Hunter K, Schorr C,
Abboud M, Henry P, Weisberg LS. The fallacy
of the BUN: creatinine ratio in critically ill patients.
Nephrol Dial Transplant 2012;27:2248–2254.
Yunos NM, Bellomo R, Hegarty C, Story D, Ho L, Bailey M.
Association between a chloride‑liberal vs
chloride‑restrictive intravenous fluid administration strategy and
kidney injury in critically ill adults. JAMA 2012;308:
1566–1572.
Shaw AD, Bagshaw SM, Goldstein SL, Scherer LA, Duan M, Schermer CR,
Kellum JA. Major complications, mortality, and resource
utilization after open abdominal surgery: 0.9% saline compared to
Plasma‑Lyte. Ann Surg 2012;255:821–829.
Ostermann M, Dickie H, Barrett NA. Renal replacement therapy in critically ill patients with acute kidney injury – when to start. Nephrol Dial Transplant 2012 (e‑pub ahead of print).
Felker GM, et al., NHLBI Heart Failure Clinical Research Network. Diuretic strategies in patients with acute decompensated heart failure. N Engl J Med 2011;364:797–805.
Singh V, Dhungana SP, Singh B, Vijayverghia R, Nain CK, Sharma N, Bhalla A, Gupta PK. Midodrine in patients with cirrhosis and refractory or recurrent ascites: a randomized pilot study. J Hepatol. 2011, doi:10.1016/j. jhep.2011.04.027
Mehta RL, Bouchard J, Soroko SB, Ikizler TA, Paganini EP, Chertow GM, Himmelfarb J, Program to Improve Care in Acute Renal Disease (PICARD) Study Group. Sepsis as a cause and consequence of acute kidney injury: Program to Improve Care in Acute Renal Disease. Intensive Care Med 2011;37:241–248.
Manno C, Bonifati C, Torres DD, Campobasso N, Schena FP. Desmopressin acetate in percutaneous ultrasound – guided kidney biopsy: A randomized controlled trial. Am J Kindey Dis 2011;57:850–855.
Eyler RF, Mueller BA. Antibiotic dosing in critically ill patients with acute kidney injury. Nat Rev Nephrol 2011;7:226–235.
Grams ME, Estrella MM, Coresh J, Brower RG, Liu KD; for the National Heart, Lung, Blood Institute Acute Respiratory Distress Syndrome Network. Fluid balance, diuretic use, and mortality in acute kidney injury. Clin J Am Soc Nephrol 2011, v tisku.
Bayer O, Reinhart K, Sakr Y, Kabisch B, Kohl M, Riedemann NC, Bauer M, Settmacher U, Hekmat K, Hartog CS. Renal effects of synthetic colloids and crystalloids in patients with severe sepsis: A prospective sequential comparison. Crit Care Med 2011, v tisku
Hetzel GR, Schmitz M, Wissing H, Ries W, Schott G, Heering PJ, Isgro F, Kribben A, Himmele R, Grabensee B, Rump LC. Regional citrate versus systemic heparin for anticoagulation in critically ill patients on continuous venovenous haemofiltration: a prospective randomized multicentre trial. Nephrol Dial Transplant 2011;26:232–239.
Faybik P, Hetz H, Mitterer G, Krenn CG, Schiefer J, Funk GC, Bacher A. Regional citrate anticoagulation in patients with liver failure supported by a molecular adsorbent recirculating system. Crit Care Med 2011;39:273–279.
Pun PH, Lehrich RW, Honeycutt EF, Herzog CA, Middleton JP. Modifiable risk factors associated with sudden cardiac arrest within hemodialysis clinics. Kidney Int 2010 Sep 1., v tisku.
Szczech LA, Granger CB, Dasta JF, Amin A, Peacock WF, McCullough PA, Devlin JW, Weir MR, Katz JN, Anderson FA Jr, Wyman A, Varon J; Studying the Treatment of Acute Hypertension Investigators. Acute kidney injury and cardiovascular outcomes in acute severe hypertension. Circulation 2010;121:2183–2191.
Stolker JM, McCullough PA, Rao S, Inzucchi SE, Spertus JA, Maddox TM, Masoudi FA, Xiao L, Kosiborod M. Pre-procedural glucose levels and the risk for contrast-induced acute kidney injury in patients undergoing coronary angiography. J Am Coll Cardiol 2010;55:1433–1440.
James MT, Wald R, Bell CM, Tonelli M, Hemmelgarn BR, Waikar SS, Chertow GM. Weekend hospital admission, acute kidney injury, and mortality. J Am Soc Nephrol 2010;21:845–851.
Cruz DN, de Cal M, Garzotto F, Perazella MA, Lentini P, Corradi V, Piccinni P, Ronco C. Plasma neutrophil gelatinase‑associated lipocalin is an early biomarker for acute kidney injury in an adult ICU population. Intensive Care Med 2010;36:444–451.
Murugan R, Karajala‑Subramanyam V, Lee M, Yende S, Kong L, Carter M, Angus DC, Kellum JA; Genetic and Inflammatory Markers of Sepsis (GenIMS) Investigators. Acute kidney injury in non‑severe pneumonia is associated with an increased immune response and lower survival. Kidney Int 2010;77:527–535.
Joannidis M, Druml W, Forni LG, Groeneveld AB, Honore P, Oudemans‑van Straaten HM, Ronco C, Schetz MR, Woittiez AJ. Prevention of acute kidney injury and protection of renal function in the intensive care unit: Expert opinion of the working group for nephrology, ESICM. Intensive Care Med 2010. Epub ahead of print.
RENAL Replacement Therapy Study Investigators, Bellomo R, Cass A, Cole L, Finfer S, Gallagher M, Lo S, McArthur C, McGuinness S, Myburgh J, Norton R, Scheinkestel C, Su S. Intensity of continuous renal‑replacement therapy in critically ill patients. N Engl J Med 2009;361:1627–1638.
Cruz DN, Antonelli M, Fumagalli R, Foltran F, Brienza N, Donati A, Malcangi V, Petrini F, Volta G, Bobbio Pallavicini FM, Rottoli F, Giunta F, Ronco C. Early use of polymyxin B hemoperfusion in abdominal septic shock: the EUPHAS randomized controlled trial. JAMA 2009;301:2445–2452.
Bouchard J, Soroko SB, Chertow GM, Himmelfarb J, Ikizler TA, Paganini EP, Mehta RL; Program to Improve Care in Acute Renal Disease (PICARD) Study Group. Fluid accumulation, survival and recovery of kidney function in critically ill patients with acute kidney injury. Kidney Int 2009;76:422–427.
Bosch X, Poch E, Grau JM. Rhabdomyolysis and acute kidney injury. N Engl J Med 2009;361:62–72.
Triverio PA, Martin PY, Romand J, Pugin J, Perneger T, Saudan P. Long‑term prognosis after acute kidney injury requiring renal replacement therapy. Nephrol Dial Transplant 2009;24:2186–2189.
Bagshaw SM, Lapinsky S, Dial S, Arabi Y, Dodek P, Wood G, Ellis P, Guzman J, Marshall J, Parrillo JE, Skrobik Y, Kumar A. Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group. Acute kidney injury in septic shock: clinical outcomes and impact of duration of hypotension prior to initiation of antimicrobial therapy. Intensive Care Med 2009;35:871–881.
Mullens W, Abrahams Z, Francis GS, Sokos G, Taylor DO, Starling RC, Young JB, Tang WH. Importance of venous congestion for worsening of renal function in advanced decompensated heart failure. J Am Coll Cardiol 2009;53:589–596.
Payen D, Mateo J, Cavaillon JM, Fraisse F, Floriot C, Vicaut E; Hemofiltration and Sepsis Group of the Collège National de Réanimation et de Médecined’Urgence des Hôpitaux extra-Universitaires. Impact of continuous venovenous hemofiltration on organ failure during the early phase of severe sepsis: a randomized controlled trial. Crit Care Med 2009;37:803–810.
Schortgen F, Girou E, Deye N, Brochard L; CRYCO Study Group. The risk associated with hyperoncotic colloids in patients with shock. Intensive Care Med 2008;34:2157–2168
van der Voort PH, Boerma EC, Koopmans M, Zandberg M, de Ruiter J, Gerritsen RT, Egbers PH, Kingma WP, Kuiper MA. Furosemide does not improve renal recovery after hemofiltration for acute renal failure in critically ill patients: A double blind randomized controlled trial. Critical Care Medicine 2009;37:533–538.